Validation of commercial dry-form panels (sensititre) for the susceptibility testing of AZD2563, a new long-acting oxazolidinone
نویسندگان
چکیده
P1045 Citation: Clinical Microbiology and Infection Volume 8, Supplement 1, 2002 Validation of commercial dry-form panels (sensititre) for the susceptibility testing of AZD2563, a new long-acting oxazolidinone R. Jones, T. Anderegg, D. Biedenbach, P. Rhomberg
منابع مشابه
Validation of a commercial dry-form broth microdilution device (Sensititre) for testing tedizolid, a new oxazolidinone.
Tedizolid, a novel oxazolidinone antibacterial with potent activity against a wide range of Gram-positive pathogens, was recently approved by regulatory authorities for the treatment of acute bacterial skin and skin structure infections. A commercial broth microdilution device (Sensititre; Thermo Fisher Scientific) was validated using 285 selected Gram-positive isolates, and the device was docu...
متن کاملValidation of Sensititre Dry-Form Broth Microdilution Panels for Susceptibility Testing of Ceftazidime-Avibactam, a Broad-Spectrum-β-Lactamase Inhibitor Combination.
Ceftazidime-avibactam is a broad-spectrum-β-lactamase inhibitor combination in late-stage clinical development for the treatment of serious infections. In preparation for clinical microbiology laboratory use, a validation experiment was initiated to evaluate a commercial broth microdilution product (Sensititre dried MIC susceptibility system) compared to reference panels using 525 recent clinic...
متن کاملActivity of AZD2563, a novel oxazolidinone, against Staphylococcus aureus strains with reduced susceptibility to vancomycin or linezolid.
The susceptibilities of clinical vancomycin-intermediate Staphylococcus aureus (VISA), heterogeneous VISA, and laboratory-generated linezolid-resistant S. aureus strains to the new oxazolidinone AZD2563 were assessed by agar dilution MIC determination. All clinical strains were susceptible to linezolid, and the linezolid MICs for them were equal to or twofold higher than those of AZD2563. Cross...
متن کاملIn vitro evaluation of AZD2563, a novel oxazolidinone, against 603 recent staphylococcal isolates.
AZD2563, a novel oxazolidinone, and a selection of comparator drugs that included linezolid, erythromycin, clindamycin, quinolones, and gentamicin were tested against 384 Staphylococcus aureus (176 oxacillin-resistant S. aureus [ORSA]) and 219 coagulase-negative staphylococci (CoNS; 162 oxacillin resistant) by reference microdilution (all strains) and agar dilution (30 strains) methods. The fol...
متن کاملAZD2563, a new oxazolidinone: bactericidal activity and synergy studies with gentamicin and vancomycin against Staphylococci and Streptococci
P754 Citation: Clinical Microbiology and Infection Volume 8, Supplement 1, 2002 AZD2563, a new oxazolidinone: bactericidal activity and synergy studies with gentamicin and vancomycin against staphylococci and streptococci R. Jones, T. Anderegg, L. Deshpande, D. Biedenbach
متن کامل